PURPOSE: To evaluate the effects of social support on comprehension and recall of consent form information in a study of Parkinson disease patients and their caregivers.DESIGN and METHODS: Comparison of comprehension and recall outcomes among participants who read and signed the consent form accompanied by a family member/friend versus those of participants who read and signed the consent form unaccompanied. Comprehension and recall of consent form information were measured at one week and one month respectively, using Part A of the (...) Quality of Informed Consent Questionnaire .RESULTS: The mean age of the sample of 143 participants was 71 years . Analysis of covariance was used to compare QuIC scores between the intervention group and control group . In the 1-week model, no statistically significant intervention effect was found . However, the intervention status by patient status interaction was statistically significant . In the 1-month model, no statistically significant intervention effect was found . Again, however, the intervention status by patient status interaction was statistically significant . At both time periods, intervention group patients scored higher on the QuIC than did intervention group caregivers, and control group patients scored lower on the QuIC than did control group caregivers.IMPLICATIONS: Social support played a significant role in enhancing comprehension and recall of consent form information among patients. (shrink)

Background The use of lengthy, detailed, and complex informed consent forms is of paramount concern in biomedical research as it may not truly promote the rights and interests of research participants. The extent of information in ICFs has been the subject of debates for decades; however, no clear guidance is given. Thus, the objective of this study was to determine the perspectives of research participants about the type and extent of information they need when they are invited to participate in (...) biomedical research. Methods This multi-center, cross-sectional, descriptive survey was conducted at 54 study sites in seven Asia-Pacific countries. A modified Likert-scale questionnaire was used to determine the importance of each element in the ICF among research participants of a biomedical study, with an anchored rating scale from 1 to 5. Results Of the 2484 questionnaires distributed, 2113 were returned. The majority of respondents considered most elements required in the ICF to be ‘moderately important’ to ‘very important’ for their decision making. Major foreseeable risk, direct benefit, and common adverse effects of the intervention were considered to be of most concerned elements in the ICF. Conclusions Research participants would like to be informed of the ICF elements required by ethical guidelines and regulations; however, the importance of each element varied, e.g., risk and benefit associated with research participants were considered to be more important than the general nature or technical details of research. Using a participant-oriented approach by providing more details of the participant-interested elements while avoiding unnecessarily lengthy details of other less important elements would enhance the quality of the ICF. (shrink)

There is currently intense interest in the question of the source of our presumed knowledge of truths concerning what is, or is not, metaphysically possible or necessary. Some philosophers locate this source in our capacities to conceive or imagine various actual or non-actual states of affairs, but this approach is open to certain familiar and seemingly powerful objections. A different and ostensibly more promising approach has been developed by Timothy Williamson, according to which our capacity for modal knowledge is just (...) an extension, or by-product, of our general capacity to acquire knowledge of true counterfactual conditionals — a capacity that we deploy ubiquitously in everyday life. Williamson’s account crucially involves a thesis to the effect that modal truths can be explained in terms of counterfactual truths. In this paper, I query Williamson’s account on a number of points, including this thesis. My positive proposal, which owes a debt to the work of Kit Fine on modality and essence, appeals instead to our capacity to grasp essences, understood in a neo-Aristotelian fashion, according to which essences are expressed by ‘real definitions’. (shrink)

Auf Kants berühmte Frage "Wie ist Metaphysik möglich?" wird eine bejahende Antwort gegeben - eine, die Metaphysik als eine selbständige und unentbehrliche Disziplin darstellt, deren Aufgabe es ist, das Reich der wirklichen Möglichkeiten zu erforschen. Die Begriffe der "wirklichen" oder "metaphysischen" Möglichkeit und Notwendigkeit werden verteidigt und von den Begriffen verschiedener anderer Arten von Modalität unterschieden, z.B. physischer, logischer und begrifflicher Möglichkeit oder Notwendigkeit. Es wird dargelegt, daß die Gegner der Metaphysik, von den Relativisten bis zu denen, welche die Metaphysik (...) den empirischen Wissenschaften, der Erkenntnislehre oder der Sprachphilosophie unterordnen möchten, inkohärente Auffassungen annehmen. (shrink)

Recently, Terry Horgan and Matjaž Potrč have defended the thesis of ‘existence monism’, according to which the whole cosmos is the only concrete object. Their arguments appeal largely to considerations concerning vagueness. Crucially, they claim that ontological vagueness is impossible, and one key assumption in their defence of this claim is that vagueness always involves ‘sorites-susceptibility’. I aim to challenge both the claim and this assumption. As a consequence, I seek to undermine their defence of existence monism and support a (...) common-sense pluralist ontology of ‘ordinary objects’ as being fully consistent with a thoroughgoing metaphysical realism. (shrink)

When, for example, we say of something that it ‘is an object’, or ‘is an event’, or ‘is a property’, we are engaging in categorial predication: we are assigning something to a certain ontological category. Ontological categorization is clearly a type of classification, but it differs radically from the types of classification that are involved in the taxonomic practices of empirical sciences, as when a physicist says of a certain particle that it ‘is an electron’, or when a zoologist says (...) of a certain animal that it ‘is a mammal’, or when a meteorologist says of a certain weather‐phenomenon that it ‘is a hurricane’. Classifications of the latter types presuppose that the items being classified have already been assigned to appropriate ontological categories, such as the categories of object, species, or event. What do categorial predications mean? How are their truth‐conditions to be determined, and how can those truth‐conditions be known to be satisfied? Do they have truthmakers? Questions like these are amongst those addressed in the present paper. (shrink)

'Object' and 'criterion of identity' are philosophical terms of art whose application lies at a considerable theoretical remove from the surface phenomena of everyday linguistic usage. This partly explains their highly controversial status, for their point of application lies precisely where the concerns of linguists and philosophers of language merge with those of metaphysicians. This chapter explains the possession of determinate identity‐conditions. It argues that the distinction between 'abstract' and 'concrete' objects is itself a highly controversial one, and although it (...) has indeed been argued that this distinction turns ultimately upon differences between the criteria of identity governing objects of these two broad categories. It examines the role which criteria of identity play in our talk about objects of the least controversial varieties. The chapter concerns the problem of identity over time and the paradoxes to which identity criteria often appear to give rise when time is brought into the picture. (shrink)

Drawing on recent scholarship, with essays by a selection of international scholars, this volume throws new light on the literary persona of Peter Abelard, one of the most diversely gifted people of the Middle Ages.

‘Water is H2O’ is one of the most frequently cited sentences in analytic philosophy, thanks to the seminal work of Saul Kripke and Hilary Putnam in the 1970s on the semantics of natural kind terms. Both of these philosophers owe an intellectual debt to the empiricist metaphysics of John Locke's Essay Concerning Human Understanding, while disagreeing profoundly with Locke about the reality of natural kinds. Locke employs an intriguing example involving water to support his view that kinds (or ‘species’), such (...) as water and gold, are the workmanship of the human mind. This is the point of his story about a winter visitor to England from Jamaica, who is astonished to find that the water in his basin has turned solid overnight, and proceeds to call it ‘hardened water’. Locke criticizes this judgement, maintaining that it is more consonant with common sense to regard water and ice as different kinds of substance. Putnam, by implication, disagrees. Deploying his imaginary example of Twin Earth—a distant planet where a watery-looking substance, XYZ, rather than H2O, fills the oceans and rivers—he maintains that common sense supports the judgement that XYZ and H2O, despite their superficial similarity, are not the same kind of substance, precisely because their molecular compositions are different. Here it will be argued that both views are mistaken, but that, in this dispute, Locke has more right on his side than his modern opponents do. (shrink)

Stephen Mumford and Rani Lill Anjum have recently attacked causal necessitarianism – the doctrine that causes necessitate their effects – on the grounds that causation does not survive what they describe as the test of antecedent strengthening. This article shows that there are credible conditional logics which do not sanction this test, thereby providing an escape route for proponents of causal necessitarianism from Mumford and Anjum's argument.

This paper has two main parts. In the first part, I argue that prominent moves in two related current debates in epistemology—viz., the debates over classical invariantism and the knowledge first movement—depend on one or the other of two claims about epistemic propriety: (1) Impropriety due to lack of a particular epistemic feature suffices for epistemic impropriety; and (2) Having justification to believe P suffices for having warrant to assert P. In the second part, I present and defend novel arguments (...) against both claims. (shrink)

Construing miracles as \textquotedblleft{}violations,\textquotedblright I argue that a law of nature must specify some kind of possibility. But we must have here a sense of possibility for which the ancient rule of logic---ab esse ad posse valet consequentia---does not hold. We already have one example associated with the concept of statute law, a law which specifies what is legally possible but which is not destroyed by a violation. If laws of nature are construed as specifying some analogous sense of what (...) is naturally possible, then they need not be invalidated by a (rare) violation, and Humean miracles remain a genuine possibility. (shrink)

Locke's main semantic thesis is that words stand for, or signify, ideas. He says this over and over again, though the phraseology he employs varies. In Book III chapter 2 alone we find the following statements of the thesis: ‘ … Words … come to be made use of by Men, as the Signs of their Ideas’ [III.2.1; 405:10-11); The use then of Words, is to be sensible Marks of Ideas; and the Ideas they stand for, are their proper and (...) immediate Signification’ [III.2.1; 405:15-17]; ‘Words in their primary or immediate Signification, stand for nothing, but the Ideas in the Mind of him that uses them’ [III.2.2; 405:21-2]; That then which Words are the Marks of, are the Ideas of the Speaker’ [III.2.2; 405:27-8]; ‘ …. (shrink)

In 1498 Cajetan published a short book, On the Analogy of Names, which is often regarded as a masterly summary of Aquinas's doctrine of analogy. It opens in the very first paragraph with an attack on three views of the concept of being (ens): first, that it is a disjunction of concepts; second, that it is an ordered group of concepts; and third, that it is a single, separate concept which is unequally participated by substances and accidents. A number of (...) questions immediately spring to mind. Why are concepts being discussed when analogy is said by Cajetan to be a theory of language? What is meant by ‘concept’? Who held the views under attack and why? So far as I can tell, the extensive literature on both Aquinas and Cajetan offers no satisfactory answers to these questions. (shrink)

To avoid the necessity of relying on trust in the matter of scientific authorship, most biomedical journals have adopted the uniform requirements for manuscripts submitted to biomedical journals, which are produced by the International Committee of Medical Journal Editors .1 The scientific journals that are members of the ICMJE routinely ask contributors to sign a statement that they accept full responsibility for the conduct of the study, had access to the data, and controlled the decision to publish. They even request (...) and publish information about the contributions of each person named as having participated.2,3 It turns out, however, that these requirements do …. (shrink)

In the Second Meditation, Descartes famously asks at one point, ‘But what then am I?’ – to which his immediate answer is ‘A thing that thinks.’ It is this question, or rather the plural version of it, that Eric Olson examines in this excellent book. He thinks that it is – today, at least – a rather neglected question. He points out that it is wrong to confuse the question with the much more frequently examined question of what personal identity (...) consists in. In fact, he thinks that possible answers to the two questions, even if not entirely independent of one other, constrain each other only to a rather limited extent. It is important to appreciate that Olson is not inquiring into what persons in general are, but only into what we human persons are. Olson explores all the major, and some of the less well-known, answers that have been offered to this question. He begins with the answer that he himself has defended in an earlier book, The Human Animal – the answer that we are human animals, that is, biological organisms of a certain kind. Indeed, Olson is, along with Peter van Inwagen, one of the best known ‘animalists’ – although he admits to being a little more tentative in his endorsement of this position now, for reasons that we shall come to later. The other views that he considers are these: that we are entities that are ‘constituted’ by, but not identical with, human animals (the view of Lynne Rudder …. (shrink)

John Heil’s new book is remarkable in many ways. In a concise, lucid and accessible manner, it develops a complete system of ontology with many strikingly original features and then applies that ontology to fundamental issues in the philosophy of mind, with illuminating results. Although Heil acknowledges his intellectual debts to C. B. Martin, he is unduly modest about his own contribution to the development and application of this novel metaphysical system. A full examination of the position that Heil defends (...) would require a book in itself, so I shall limit myself to discussing some of its central themes and to explaining a few doubts that I have concerning some aspects of it. (shrink)